![]() ![]() This study estimates 37 000 US patients with RP incidence was 6.0/100 000/year (95% CI, 5.6‒6.3), and prevalence was 11.2/100 000 (95% CI, 10.6‒11.7).Īcute pericarditis is often associated with severe symptoms, including sharp, pleuritic chest pain and dyspnea. Pharmacotherapy included colchicine (51%), NSAIDs (40%), and corticosteroids (30%), often in combination. ![]() ![]() Complications included pericardial effusion (50%), cardiac tamponade (9%), and constrictive pericarditis (4%). Patients (N=2096) had hypertension (60%), cardiomegaly (9%), congestive heart failure (17%), atrial fibrillation (16%), autoimmune diseases (18%), diabetes mellitus (21%), renal disease (20%), anxiety (21%), and depression (14%). Among these patients with multiple recurrences and/or complications, some had features relating to treatment history, including long‐term corticosteroid use (corticosteroids started within 30 days of flare, continuing ≥90 consecutive days) or inadequate treatment response (pericarditis recurring despite corticosteroids and/or colchicine, or other drugs within 30 days of flare, or prior pericardiectomy). Some patients had ≥2 recurrences, while others had a single recurrence with a serious complication, ie, constrictive pericarditis, cardiac tamponade, or a large pericardial effusion with pericardiocentesis/pericardial window. RP was defined as ≥2 pericarditis episodes ≥28 days apart. This retrospective US database analysis included newly diagnosed patients with RP with ≥24 months of continuous history following their first pericarditis episode. ![]()
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